one. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This is often an impurity related to bortezomib, a proteasome inhibitor Employed in the treatment of various myeloma. Its synthesis or review is important for guaranteeing the purity and safety of the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor from the synthesis of abiraterone acetate, a drug Utilized in the treatment of prostate cancer by inhibiting androgen production.
Imatinib Intermediate (CAS NO. 152460-ten-1): A vital compound inside the synthesis of imatinib, a drug that targets particular forms of most cancers, such as Serious myelogenous leukemia (CML).
Docetaxel Intermediate: A compound used in the synthesis of docetaxel, a chemotherapy medication that treats many cancers for example breast, lung, and prostate cancer.
two. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, 8): These are intermediates from the synthesis of gemcitabine, an anti-most cancers drug. Their examine is essential for optimizing the creation process and making certain substantial purity.
Lapatinib Intermediate Abiraterone Acetate Intermediate (CAS NO. 231278-eighty four-5): Lapatinib is utilised to take care of breast most cancers, and these intermediates are involved in its creation.
Fulvestrant Intermediates: Fulvestrant can be an estrogen receptor antagonist Employed in the therapy of breast cancer. Many intermediates assist in the synthesis of this drug.
Paclitaxel Side Chain Acid (CAS NO. 949023-16-9): This intermediate is Employed in the synthesis of paclitaxel, a chemotherapy drug efficient in dealing with cancers for example ovarian, breast, and lung most cancers.
three. Other Noteworthy Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-three): A chemotherapy drug Utilized in the procedure of colorectal most cancers and little cell lung cancer.
3-Amino-1-hydroxyadamantane (CAS 702-82-nine): This compound is linked to the synthesis of adamantane derivatives, that have many purposes, including antiviral properties.
Vildagliptin Intermediates: Used in the production of vildagliptin, an oral drug for kind two diabetic issues that inhibits the enzyme DPP-four to manage blood sugar stages.
4. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-48-1): This compound is linked TBTU to the synthesis of assorted gluconic acid derivatives, which are Employed in food items, pharmaceutical, and industrial apps.
Canagliflozin Intermediate 2: A precursor inside the synthesis of canagliflozin, a medication employed to handle type two diabetic issues by inhibiting sodium-glucose co-transporter 2 (SGLT2).